Purifying Active Ingredients for the Life Sciences industries
These mixtures typically possess one or more of the following chemical characteristics:
A Natural Chemical Backbone
One or More Asymmetric Centers
A Molecular Weight usually Greater than 300 Dalton (g/mol)
We specialize in purifying active ingredients that cannot be synthesized, extracted, or produced in pure form using conventional chemistry and biotechnology.
These target molecules require separation from structurally similar molecules, forming what we term as complex mixtures.
Typical Ingredients for Cromaoak’s Process
Plant extracts
Fatty acids
For example : EPA, DHA
Peptides & Proteins
Insulin and analogues
Oligonucleotides
Vaccines
ADC (Antibody-drug conjugates)
Cytotoxic, Anti-cancer drugs
These active ingredients are invaluable to industries such as :
- Pharmaceuticals,
- Cosmetics,
- Flavors and fragrances,
- Nutraceuticals.
Application Note:
Introduction to Multi-Frequency Chromatography
Multifrequency chromatography is a straightforward, intensified process that can be implemented on a single column managed by a standard HPLC system. This innovative downstream process is designed for the purification of complex mixtures, from lab to industrial scale, and its excellent performance leads to OPEX and CAPEX optimizations